CCNT1 Antibody
Produktgrößen
100ul
£630,00
OAGA08209-100UL
Über dieses Produkt
- SKU:
- OAGA08209
- Zusätzliche Namen:
- CCNT; CYCT1; HIVE1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9; and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans; there are multiple forms of positive transcription elongation factor b; which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein; and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.
- Gendetails:
- cyclin T1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Cyclin T1. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- cyclin-T1
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php