DNMT3L Antibody
Produktgrößen
100ul
£630,00
OAGA05259-100UL
Über dieses Produkt
- SKU:
- OAGA05259
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CpG methylation is an epigenetic modification that is important for embryonic development; imprinting; and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases; but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However; it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- DNA methyltransferase 3 like
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human DNMT3L. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- DNA (cytosine-5)-methyltransferase 3-like
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php