EWSR1 Antibody
Produktgrößen
100ul
£630,00
OAGA04512-100UL
Über dieses Produkt
- SKU:
- OAGA04512
- Zusätzliche Namen:
- EWS; EWS-FLI1; bK984G1.4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.66 mg/ml
- Weitere Details:
- This gene encodes a multifunctional protein that is involved in various cellular processes; including gene expression; cell signaling; and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene; specifically a t(11;22)(q24;q12) translocation; are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
- Gendetails:
- EWS RNA binding protein 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human EWSR1. The exact sequence is proprietary.
- Isotyp:
- IgG
- Molekulargewicht:
- 68 kDa
- Proteindetails:
- RNA-binding protein EWS
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks); store at 4°C. For long-term storage; aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php