ERN1 Antibody - N-terminal region
Produktgrößen
100ul
£630,00
OAGA04398-100UL
Über dieses Produkt
- SKU:
- OAGA04398
- Zusätzliche Namen:
- IRE1; IRE1P; IRE1a; hIRE1p
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains; a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins; regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1.
- Gendetails:
- endoplasmic reticulum to nucleus signaling 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human IRE1 alpha. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- serine/threonine-protein kinase/endoribonuclease IRE1
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php