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Antikörper

GAD1 Antibody

Produktgrößen
100ul
£630,00
OAGA04236-100UL
Über dieses Produkt
SKU:
OAGA04236
Zusätzliche Namen:
GAD; SCP; CPSQ1; DEE89
Klonalität:
Polyclonal
Konzentration:
0.53 mg/ml
Weitere Details:
This gene encodes one of several forms of glutamic acid decarboxylase; identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products; the predominant 67-kD form and a less-frequent 25-kD form.
Gendetails:
glutamate decarboxylase 1
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human GAD67. The exact sequence is proprietary.
Isotyp:
IgG
Proteindetails:
glutamate decarboxylase 1
Aufreinigung:
Purified by antigen-affinity chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody