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Antikörper

CASP10 Antibody

Produktgrößen
100ul
£630,00
OAGA04219-100UL
Über dieses Produkt
SKU:
OAGA04219
Zusätzliche Namen:
MCH4; ALPS2; FLICE2; FLICE-2
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7; and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome; non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gendetails:
caspase 10
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Caspase 10. The exact sequence is proprietary.
Isotyp:
IgG
Proteindetails:
caspase-10
Aufreinigung:
Purified by antigen-affinity chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody