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Antikörper

DAXX Antibody

Produktgrößen
100ul
£630,00
OAGA04144-100UL
Über dieses Produkt
SKU:
OAGA04144
Zusätzliche Namen:
DAP6; EAP1; BING2; SMIM40
Klonalität:
Polyclonal
Konzentration:
0.63 mg/ml
Weitere Details:
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins; such as apoptosis antigen Fas; centromere protein C; and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus; the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm; the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications; including sumoylation; phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Gendetails:
death domain associated protein
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Daxx. The exact sequence is proprietary.
Isotyp:
IgG
Proteindetails:
death domain-associated protein 6
Aufreinigung:
Purified by antigen-affinity chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody