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Antikörper

COL1A1 Antibody - N-terminal region

Produktgrößen
100ul
£630,00
OAGA04105-100UL
Über dieses Produkt
SKU:
OAGA04105
Zusätzliche Namen:
OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1
Klonalität:
Polyclonal
Konzentration:
0.1 mg/ml
Weitere Details:
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone; cornea; dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV; Ehlers-Danlos syndrome type VIIA; Ehlers-Danlos syndrome Classical type; Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22; where this gene and the gene for platelet-derived growth factor beta are located; are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans; resulting from unregulated expression of the growth factor. Two transcripts; resulting from the use of alternate polyadenylation signals; have been identified for this gene.
Gendetails:
collagen type I alpha 1 chain
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human COL1A1. The exact sequence is proprietary.
Isotyp:
IgG
Proteindetails:
collagen alpha-1(I) chain
Aufreinigung:
Purified by antigen-affinity chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody