CKMT1B Antibody
Produktgrößen
100ul
£630,00
OAGA03998-100UL
Über dieses Produkt
- SKU:
- OAGA03998
- Zusätzliche Namen:
- CKMT; CKMT1; UMTCK
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier; creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes; sarcomeric MtCK and ubiquitous MtCK; encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers; in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
- Gendetails:
- creatine kinase; mitochondrial 1B
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Creatine kinase MT. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- creatine kinase U-type; mitochondrial
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php