ERBB4 Antibody
Produktgrößen
100ul
£630,00
OAGA03762-100UL
Über dieses Produkt
- SKU:
- OAGA03762
- Zusätzliche Namen:
- HER4; ALS19; p180erbB4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.95 mg/ml
- Weitere Details:
- This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains; a transmembrane domain; a tyrosine kinase domain; a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however; not all variants have been fully characterized.
- Gendetails:
- erb-b2 receptor tyrosine kinase 4
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human ERBB4. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- receptor tyrosine-protein kinase erbB-4
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php