CFHR5 Antibody
Produktgrößen
100ul
£630,00
OAGA03498-100UL
Über dieses Produkt
- SKU:
- OAGA03498
- Zusätzliche Namen:
- FHR5; CFHL5; FHR-5; CFHR5D
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties; a region within repeats 5-7 having heparin binding and C reactive protein binding properties; and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3; binds C3b in a dose-dependent manner; and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated; but not causally linked; with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
- Gendetails:
- complement factor H related 5
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human CFHR5. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- complement factor H-related protein 5
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php