DUSP9 Antibody - C-terminal region
Produktgrößen
100ul
£630,00
OAGA03370-100UL
Über dieses Produkt
- SKU:
- OAGA03370
- Zusätzliche Namen:
- MKP4; MKP-4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK; SAPK/JNK; p38); which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases; different tissue distribution and subcellular localization; and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.
- Gendetails:
- dual specificity phosphatase 9
- Host:
- Rabbit
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MKP4. The exact sequence is proprietary.
- Isotyp:
- IgG
- Proteindetails:
- dual specificity protein phosphatase 9
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php