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Antikörper

FDPS Antibody

Produktgrößen
100ul
£630,00
OAGA02517-100UL
Über dieses Produkt
SKU:
OAGA02517
Zusätzliche Namen:
FPS; FPPS; POROK9
Klonalität:
Polyclonal
Konzentration:
0.75mg/ml
Weitere Details:
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product; farnesyl pyrophosphate; is a key intermediate in cholesterol and sterol biosynthesis; a substrate for protein farnesylation and geranylgeranylation; and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1; 7; 14; 15; 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Gendetails:
farnesyl diphosphate synthase
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human FDPS. The exact sequence is proprietary.
Isotyp:
IgG
Molekulargewicht:
48 kDa
Aufreinigung:
Purified by antigen-affinity chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody