APLP2 Antibody - N-terminal region
Produktgrößen
100ul
£630,00
OAGA01781-100UL
Über dieses Produkt
- SKU:
- OAGA01781
- Zusätzliche Namen:
- APPH; APPL2; CDEBP; APLP-2
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2); which is a member of the APP (amyloid precursor protein) family including APP; APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-; copper- and zinc- binding domains at the N-terminus; BPTI/Kunitz inhibitor and E2 domains in the middle region; and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission; spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Gendetails:
- amyloid beta (A4) precursor-like protein 2
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human APLP2. The exact sequence is proprietary.
- Isotyp:
- IgG
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php