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Antikörper

ENSA Antibody

Produktgrößen
100ul
£630,00
OAGA01615-100UL
Über dieses Produkt
SKU:
OAGA01615
Zusätzliche Namen:
ARPP-19e
Klonalität:
Polyclonal
Konzentration:
0.6mg/ml
Weitere Details:
The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor; ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel; which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel; and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gendetails:
endosulfine alpha
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human ENSA. The exact sequence is proprietary.
Isotyp:
IgG
Aufreinigung:
Purified by antigen-affinity chromatography.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody