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Antikörper

CSTB Antibody

Produktgrößen
100ul
£630,00
OAGA01600-100UL
Über dieses Produkt
SKU:
OAGA01600
Zusätzliche Namen:
PME; ULD; CST6; EPM1; STFB; CPI-B; EPM1A
Klonalität:
Polyclonal
Konzentration:
6.04mg/ml
Weitere Details:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors; while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily; including the type 1 cystatins (stefins); type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces; inhibiting papain and cathepsins l; h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Gendetails:
cystatin B (stefin B)
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Cystatin B. The exact sequence is proprietary.
Isotyp:
IgG
Aufreinigung:
Affinity purified by Protein A.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody