DMPK Antibody
Produktgrößen
100ul
£630,00
OAGA01529-100UL
Über dieses Produkt
- SKU:
- OAGA01529
- Zusätzliche Namen:
- DM; DM1; DMK; MDPK; DM1PK; MT-PK
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin; the beta-subunit of the L-type calcium channels; and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5;000 copies causes myotonic dystrophy type I; which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described; but the full-length nature of some of these variants has not been determined.
- Gendetails:
- dystrophia myotonica-protein kinase
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human DMPK. The exact sequence is proprietary.
- Isotyp:
- IgG
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php