ABAT Antibody
Produktgrößen
100ul
£630,00
OAGA01301-100UL
Über dieses Produkt
- SKU:
- OAGA01301
- Zusätzliche Namen:
- GABAT; NPD009; GABA-AT
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA); an important; mostly inhibitory neurotransmitter in the central nervous system; into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation; hypotonia; hyperreflexia; lethargy; refractory seizures; and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
- Gendetails:
- 4-aminobutyrate aminotransferase
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ABAT. The exact sequence is proprietary.
- Isotyp:
- IgG
- Aufreinigung:
- Purified by antigen-affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php