CYCS Antibody
Produktgrößen
100ug
£522,00
OAEG00823-100UG
Über dieses Produkt
- SKU:
- OAEG00823
- Zusätzliche Namen:
- CYC; HCS; THC4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex; the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9; which then accelerates apoptosis by activating other caspases. Defects in CYCS are the cause of thrombocytopenia type 4 (THC4) also known as autosomal dominant thrombocytopenia type 4. Thrombocytopenia is the presence of relatively few platelets in blood. THC4 is a non-syndromic form of thrombocytopenia. Clinical manifestations of thrombocytopenia are absent or mild. THC4 may be caused by dysregulated platelet formation.
- Gendetails:
- Cytochrome c; Cytochrome c; somatic
- Host:
- Sheep
- Immunogen:
- Full length recombinant Cytochrome C
- Isotyp:
- IgG
- Molekulargewicht:
- 14 kDa
- Aufreinigung:
- Ammonium Sulfate Precipitation
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php