CD44 Antibody
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100 tests (T100)
£441,00
OAEE00868-100TESTS
Über dieses Produkt
- SKU:
- OAEE00868
- Zusätzliche Namen:
- CD44 antigen;CDW44;cell surface glycoprotein CD44;chondroitin sulfate proteoglycan 8;CSPG8;ECMR-III;epican;extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HCELL;hematopoietic cell E- and L-selectin ligand;heparan sulfate proteoglycan;Hermes antigen;homing function and Indian blood group system;HUTCH-I;hyaluronate receptor;IN;Indian blood group antigen;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;phagocytic glycoprotein 1;Phagocytic glycoprotein I;soluble CD44.
- translate.label.attr.clone:
- MEM-85
- Klonalität:
- Monoclonal
- Konjugat:
- R-PE
- Konzentration:
- 20 ul / test
- Weitere Details:
- Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA; and possibly also through its affinity for other ligands such as osteopontin; collagens; and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration; tumor growth and progression. In cancer cells; may play an important role in invadopodia formation. Also involved in lymphocyte activation; recirculation and homing; and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter; leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
- Gendetails:
- CD44 molecule (Indian blood group)
- Host:
- Mouse
- Immunogen:
- Leukocytes of a patient suffering from LGL Type Leukaemia.
- Isotyp:
- IgG2b
- Proteindetails:
- CD44 antigen
- Aufreinigung:
- Purified by size-exclusion chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php