DPP4 Antibody
Produktgrößen
100 tests (T100)
£441,00
OAEE00754-100TESTS
Über dieses Produkt
- SKU:
- OAEE00754
- Zusätzliche Namen:
- ADABP;ADCP2;ADCP-2;adenosine deaminase complexing protein 2;CD26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;dipeptidylpeptidase 4;dipeptidylpeptidase IV (CD26; adenosine deaminase complexing protein 2);DPP IV;DPPIV;Gly-Pro naphthylamidase;Post-proline dipeptidyl aminopeptidase IV;T-cell activation antigen CD26;TP103;Xaa-Pro-dipeptidylaminopeptidase.
- translate.label.attr.clone:
- BA5b
- Klonalität:
- Monoclonal
- Konjugat:
- R-PE
- Konzentration:
- 20 ul / test
- Weitere Details:
- Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation; by binding at least ADA; CAV1; IGF2R; and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM); the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion; migration and tube formation. When overexpressed; enhanced cell proliferation; a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation; including many chemokines; mitogenic growth factors; neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
- Gendetails:
- dipeptidyl peptidase 4
- Host:
- Mouse
- Immunogen:
- A human T cell clone
- Isotyp:
- IgG2a
- Proteindetails:
- Dipeptidyl peptidase 4
- Aufreinigung:
- Purified by size-exclusion chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php