CD22 Antibody
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100 tests (T100)
£413,00
OAEE00731-100TESTS
Über dieses Produkt
- SKU:
- OAEE00731
- Zusätzliche Namen:
- B-cell receptor CD22;BL-CAM;B-lymphocyte cell adhesion molecule;CD22 antigen;sialic acid-binding Ig-like lectin 2;SIGLEC2;SIGLEC-2;T-cell surface antigen Leu-14.
- translate.label.attr.clone:
- IS7
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Konzentration:
- 20 ul / test
- Weitere Details:
- Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2;6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- Gendetails:
- CD22 molecule
- Host:
- Mouse
- Immunogen:
- human cell line Reh
- Isotyp:
- IgG1
- Proteindetails:
- B-cell receptor CD22
- Aufreinigung:
- Purified by size-exclusion chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php