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Antikörper

FASLG Antibody

Produktgrößen
100 tests (T100)
£441,00
OAEE00681-100TESTS
Über dieses Produkt
SKU:
OAEE00681
Zusätzliche Namen:
ALPS1B;apoptosis (APO-1) antigen ligand 1;apoptosis antigen ligand;APT1LG1;APTL;CD178;CD95 ligand;CD95L;CD95-L;fas antigen ligand;Fas ligand (TNF superfamily; member 6);FASL;mutant tumor necrosis factor family member 6;TNFSF6;TNLG1A;tumor necrosis factor ligand 1A;tumor necrosis factor ligand superfamily member 6.
translate.label.attr.clone:
NOK-1
Klonalität:
Monoclonal
Konjugat:
R-PE
Konzentration:
10 ul / test
Weitere Details:
Cytokine that binds to TNFRSF6/FAS; a receptor that transduces the apoptotic signal into cells (PubMed:26334989; PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis; natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058; PubMed:7528780; PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3; a decoy receptor that blocks apoptosis (PubMed:27806260).
Gendetails:
Fas ligand
Host:
Mouse
Immunogen:
L5178Y mouse T lymphoma cells expressing recombinant human CD178
Isotyp:
IgG1
Proteindetails:
Tumor necrosis factor ligand superfamily member 6
Aufreinigung:
Purified by size-exclusion chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody