CD14 Antibody
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100 tests (T100)
£441,00
OAEE00640-100TESTS
Über dieses Produkt
- SKU:
- OAEE00640
- Zusätzliche Namen:
- monocyte differentiation antigen CD14;myeloid cell-specific leucine-rich glycoprotein.
- translate.label.attr.clone:
- MEM-15
- Klonalität:
- Monoclonal
- Konjugat:
- PerCP
- Konzentration:
- 10 ul / test
- Weitere Details:
- Coreceptor for bacterial lipopolysaccharide (PubMed:1698311; PubMed:23264655). In concert with LBP; binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex; thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493; PubMed:23264655). Acts via MyD88; TIRAP and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides; these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (PubMed:23880187).
- Gendetails:
- CD14 molecule
- Host:
- Mouse
- Immunogen:
- A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
- Isotyp:
- IgG1
- Proteindetails:
- Monocyte differentiation antigen CD14
- Aufreinigung:
- Purified by size-exclusion chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php