BCL2 Antibody
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100 tests (T100)
£441,00
OAEE00573-100TESTS
Über dieses Produkt
- SKU:
- OAEE00573
- Zusätzliche Namen:
- apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
- translate.label.attr.clone:
- Bcl2/100
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Konzentration:
- 4 ul / test
- Weitere Details:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
- Gendetails:
- BCL2 apoptosis regulator
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to the amino acids 41-54 of human Bcl2
- Isotyp:
- IgG1
- Proteindetails:
- Apoptosis regulator Bcl-2
- Aufreinigung:
- Purified by size-exclusion chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php