CD6 Antibody
Produktgrößen
0.1 mg (C100)
£326,00
OAEE00288-0.1MG
Über dieses Produkt
- SKU:
- OAEE00288
- Zusätzliche Namen:
- CD6 antigen;T12;T-cell differentiation antigen CD6;TP120.
- translate.label.attr.clone:
- MEM-98
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703; PubMed:15294938; PubMed:16352806; PubMed:16914752; PubMed:24945728; PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938; PubMed:16352806; PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938; PubMed:16352806). Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria (PubMed:17601777). LPS binding leads to the activation of signaling cascades and down-stream MAP kinases (PubMed:17601777). Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS (PubMed:17601777).
- Gendetails:
- CD6 molecule
- Host:
- Mouse
- Immunogen:
- Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).
- Isotyp:
- IgG1
- Proteindetails:
- T-cell differentiation antigen CD6
- Reinheit:
- > 95% (by SDS-PAGE)
- Aufreinigung:
- Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php