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Antikörper

CD55 Antibody

Produktgrößen
0.1 mg (C100)
£398,00
OAEE00279-0.1MG
Über dieses Produkt
SKU:
OAEE00279
Zusätzliche Namen:
CD55 antigen;CD55 molecule; decay accelerating factor for complement (Cromer blood group);CHAPLE;complement decay-accelerating factor;CR;CROM;Cromer blood group antigen;DAF;Rh blood group D antigen;TC.
translate.label.attr.clone:
MEM-118
Klonalität:
Monoclonal
Konjugat:
Biotin
Konzentration:
1 mg/ml
Weitere Details:
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb; the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases; which prevents complement damage (PubMed:28657829).
Gendetails:
CD55 molecule (Cromer blood group)
Host:
Mouse
Immunogen:
HPB-ALL human T cell line
Isotyp:
IgM
Proteindetails:
Complement decay-accelerating factor
Aufreinigung:
Purified by size-exclusion chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody