FAM175A Antibody
Produktgrößen
0.1 mg (C100)
£398,00
OAEE00003-0.1MG
Über dieses Produkt
- SKU:
- OAEE00003
- Zusätzliche Namen:
- ABRA1;abraxas protein;BRCA1-A complex subunit Abraxas 1;CCDC98;coiled-coil domain containing 98;Coiled-coil domain-containing protein 98;FAM175A;family with sequence similarity 175 member A;Protein FAM175A.
- translate.label.attr.clone:
- ABRA1-01
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex; acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites; leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
- Gendetails:
- abraxas 1; BRCA1 A complex subunit
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
- Isotyp:
- IgG
- Proteindetails:
- BRCA1-A complex subunit Abraxas 1
- Reinheit:
- > 95% (by SDS-PAGE)
- Aufreinigung:
- Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php