Anti-SARM
Produktgrößen
100 ug
£615,00
OAED00366-100UG
Über dieses Produkt
- SKU:
- OAED00366
- Zusätzliche Namen:
- hSARM1;HsTIR;MyD88-5;NAD(+) hydrolase SARM1;NADase SARM1;NADP(+) hydrolase SARM1;SAM domain-containing protein 2;SAMD2;SARM;sterile alpha and Armadillo repeat protein;sterile alpha and HEAT/Armadillo motif protein; ortholog of Drosophila;sterile alpha and TIR motif-containing protein 1;sterile alpha motif domain-containing protein 2;tir-1 homolog.
- translate.label.attr.clone:
- Sarmy-1
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1; TRIF-dependent activation of NF-kappa-B and IRF3; and the phosphorylation of MAPK14/p38.
- Gendetails:
- sterile alpha and TIR motif containing 1
- Host:
- Mouse
- Immunogen:
- Recombinant human SARM (aa 93-292).
- Isotyp:
- IgG2b
- Proteindetails:
- Sterile alpha and TIR motif-containing protein 1
- Aufreinigung:
- Purified from concentrated hybridoma tissue culture supernatant
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store short-term at 4°C and long-term at -20°C. Stable for at least 1 year after receipt when stored at -20°C.
Avoid freeze/thaw cycles. - Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php