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Antikörper

Anti-FasL

Produktgrößen
100 ug
£550,00
OAED00291-100UG
Über dieses Produkt
SKU:
OAED00291
Zusätzliche Namen:
APT1;APT1LG1;CD178;CD95;CD95 ligand;CD95L;CD95-L;F;Fa;Fas antigen ligand;Fas-L;Faslg;generalized lymphoproliferative disease;gld;Tnfs;Tnfsf6;Tnlg1a;tumor necrosis factor ligand 1a;tumor necrosis factor ligand superfamily member 6.
translate.label.attr.clone:
A11
Klonalität:
Monoclonal
Konzentration:
1mg/ml
Weitere Details:
Cytokine that binds to TNFRSF6/FAS; a receptor that transduces the apoptotic signal into cells (PubMed:7511063). Involved in cytotoxic T-cell-mediated apoptosis; natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494; PubMed:7532682). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162). Binds to TNFRSF6B/DcR3; a decoy receptor that blocks apoptosis (By similarity).
Gendetails:
Fas ligand (TNF superfamily; member 6)
Host:
Rat
Immunogen:
Synthetic peptide corresponding to aa 196-220 of mouse FasL (CD95L; APO-1L; CD178).
Isotyp:
IgM
Proteindetails:
Tumor necrosis factor ligand superfamily member 6
Reinheit:
≥95% (SDS-PAGE).
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Long Term Storage : +4C
Handling : Do not freeze/thaw.
Stable for at least 6 months after receipt when stored at +4C undiluted.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody