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Antikörper

DLG4 Antibody

Produktgrößen
100 ug
£539,00
OAED00229-100UG
Über dieses Produkt
SKU:
OAED00229
Zusätzliche Namen:
discs large homolog 4;discs; large homolog 4;disks large homolog 4;Dlgh;Dlgh4;postsynaptic density protein 95;PSD;PSD-;PSD95;PSD-95;PSD-95 alpha 2b;PSD-95 beta;SA;SAP90;SAP-90;SAP90A;synapse-associated protein 90.
translate.label.attr.clone:
7E3-1B8
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable).
Gendetails:
discs large MAGUK scaffold protein 4
Host:
Mouse
Immunogen:
Recombinant rat PSD-95.
Isotyp:
IgG2a
Proteindetails:
Disks large homolog 4
Aufreinigung:
Protein G affinity purified.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Shipped on Blue Ice. For long term storage; store at -20C.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody