CD40 Antibody - PE Conjugated
Produktgrößen
1 mL
£630,00
OADB00194-1ML
Über dieses Produkt
- SKU:
- OADB00194
- Zusätzliche Namen:
- p50; Bp50; CDW40; TNFRSF5
- translate.label.attr.clone:
- B-B20
- Klonalität:
- Monoclonal
- Konjugat:
- PE: Phycoerythrin
- Konzentration:
- 100 tests/1mL
- Weitere Details:
- This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching; memory B cell development; and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand; which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation; and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Gendetails:
- CD40 molecule
- Host:
- Human
- Isotyp:
- Mouse IgG2
- Molekulargewicht:
- 31 kDa
- Proteindetails:
- tumor necrosis factor receptor superfamily member 5
- Aufreinigung:
- Ion exchange chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Reconstitute with 1 mL deionised water
Use 10 uL to label 106 cells or 100 uL of whole blood. Stable at +2-8C for six months after reconstitution. DO NOT FREEZE - Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php