CD253 Antibody
Produktgrößen
200 ug
£608,00
OADB00133-200UG
Über dieses Produkt
- SKU:
- OADB00133
- Zusätzliche Namen:
- TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
- translate.label.attr.clone:
- B-S23
- Klonalität:
- Monoclonal
- Konzentration:
- 1 ug/uL
- Weitere Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1; TNFRSF10B/TRAILR2; TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK; caspase 8; and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- tumor necrosis factor superfamily member 10
- Host:
- Mouse
- Isotyp:
- IgG1
- Molekulargewicht:
- 33 kDa
- Proteindetails:
- tumor necrosis factor ligand superfamily member 10
- Aufreinigung:
- Ion exchange chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Stable at +2-8C for 12 months. For longer storage; freeze aliquots
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php