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Antikörper

CD16 Antibody - FITC Conjugated

Produktgrößen
1 mL
£608,00
OADB00080-1ML
Über dieses Produkt
SKU:
OADB00080
Zusätzliche Namen:
CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
translate.label.attr.clone:
B-E16
Klonalität:
Monoclonal
Konjugat:
FITC: Fluorescein Isothiocyanate
Konzentration:
100 tests/1mL
Weitere Details:
This gene encodes a receptor for the Fc portion of immunoglobulin G; and it is involved in the removal of antigen-antibody complexes from the circulation; as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide; whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections; susceptibility to systemic lupus erythematosus; and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gendetails:
Fc fragment of IgG receptor IIIa
Host:
Mouse
Isotyp:
IgG2a
Molekulargewicht:
29 kDa
Proteindetails:
low affinity immunoglobulin gamma Fc region receptor III-A
Aufreinigung:
Ion exchange chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Stable at +2-8C for 12 months. For longer storage; freeze aliquots
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody