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Antikörper

CD130 Antibody

Produktgrößen
2 mL
£641,00
OADB00057-2ML
Über dieses Produkt
SKU:
OADB00057
Zusätzliche Namen:
CD130; GP130; HIES4; CDW130; IL-6RB; sGP130
translate.label.attr.clone:
B-R3
Klonalität:
Monoclonal
Konzentration:
200 tests/2mL
Weitere Details:
The protein encoded by this gene is a signal transducer shared by many cytokines; including interleukin 6 (IL6); ciliary neurotrophic factor (CNTF); leukemia inhibitory factor (LIF); and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6; a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus; can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Gendetails:
interleukin 6 signal transducer
Host:
Mouse
Isotyp:
IgG2a
Molekulargewicht:
104 kDa
Proteindetails:
interleukin-6 receptor subunit beta
Aufreinigung:
Ion exchange chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Stable at +2-8C for 12 months. For longer storage; freeze aliquots
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody