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Antikörper

CD10 Antibody

Produktgrößen
2 mL
£641,00
OADB00006-2ML
Über dieses Produkt
SKU:
OADB00006
Zusätzliche Namen:
NEP; SFE; CD10; CALLA; CMT2T; SCA43
translate.label.attr.clone:
B-E3
Klonalität:
Monoclonal
Konzentration:
200 tests/2mL
Weitere Details:
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype; which represent 85% of cases of ALL. This protein is not restricted to leukemic cells; however; and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney; where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon; enkephalins; substance P; neurotensin; oxytocin; and bradykinin. This gene; which encodes a 100-kD type II transmembrane glycoprotein; exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced; resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
Gendetails:
membrane metallo-endopeptidase
Host:
Mouse
Isotyp:
IgG2a
Molekulargewicht:
86 kDa
Proteindetails:
neprilysin
Aufreinigung:
Ion exchange chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Stable at +2-8C for 12 months. For longer storage; freeze aliquots
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody