FLT4 Antibody
Produktgrößen
100ul
£326,00
OACD08220-100UL
1ml
£912,00
OACD08220-1ML
Über dieses Produkt
- SKU:
- OACD08220
- Zusätzliche Namen:
- AI323512;Chy;chylous ascites;Flt-;Flt-4;Fms-like tyrosine kinase 4;receptor protein tyrosine kinase;tyrosine-protein kinase receptor FLT4;vascular endothelial growth factor receptor 3;VEGF;VEGFR;VEGFR3;VEGFR-3.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD; and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation; survival and migration of endothelial cells; and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC; and to a lesser degree VEGFA; thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. Mediates activation of the MAPK1/ERK2; MAPK3/ERK1 signaling pathway; of MAPK8 and the JUN signaling pathway; and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1; the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185'; and of AKT1 at 'Ser-473'.
- Gendetails:
- FMS-like tyrosine kinase 4
- Host:
- Rabbit
- Immunogen:
- Range: Pro30 - Ile326
- Isotyp:
- IgG
- Molekulargewicht:
- 153 kDa
- Proteindetails:
- Vascular endothelial growth factor receptor 3
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php