EPAS1 Antibody
Produktgrößen
100ul
£333,00
OACD04187-100UL
1ml
£933,00
OACD04187-1ML
Über dieses Produkt
- SKU:
- OACD04187
- Zusätzliche Namen:
- basic-helix-loop-helix-PAS protein MOP2;bHLHe73;class E basic helix-loop-helix protein 73;ECYT4;endothelial PAS domain-containing protein 1;EPAS-1;HIF-1alpha-like factor;HIF-1-alpha-like factor;HIF2A;HIF2-alpha;HIF-2-alpha;HLF;hypoxia-inducible factor 2 alpha;Hypoxia-inducible factor 2-alpha;member of PAS protein 2;MOP2;PAS domain-containing protein 2;PASD2.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
- Gendetails:
- endothelial PAS domain protein 1
- Host:
- Rabbit
- Immunogen:
- Range: Cys339 - Gln541
- Isotyp:
- IgG
- Molekulargewicht:
- 96 kDa
- Proteindetails:
- Endothelial PAS domain-containing protein 1
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php