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Antikörper

GSAP Antibody

Produktgrößen
100ul
£359,00
OACD04022-100UL
1ml
£1016,00
OACD04022-1ML
Über dieses Produkt
SKU:
OACD04022
Zusätzliche Namen:
gamma-secretase-activating protein;pigeon homolog;PION;protein pigeon homolog.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Regulator of gamma-secretase activity; which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42); without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta; while it reduces the epsilon-cleavage of APP CTF-alpha; leading to a low production of AICD.
Gendetails:
gamma-secretase activating protein
Host:
Rabbit
Immunogen:
Range: Asp616 - Leu854
Isotyp:
IgG
Molekulargewicht:
29 kDa
Proteindetails:
Gamma-secretase-activating protein
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody