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Antikörper

GREM1 Antibody

Produktgrößen
100ul
£355,00
OACD03987-100UL
1ml
£1005,00
OACD03987-1ML
Über dieses Produkt
SKU:
OACD03987
Zusätzliche Namen:
Cktsf1b1;cysteine knot superfamily 1; BMP antagonist 1;down-regulated in Mos-transformed cells protein;drm;gremlin 1 homolog; cysteine knot superfamily;gremlin-1.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis; as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (PubMed:15528323). Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.
Gendetails:
gremlin 1; DAN family BMP antagonist
Host:
Rabbit
Immunogen:
Recombinant GREM1 (Lys25~Asp184) expressed in E.coli.
Isotyp:
IgG
Molekulargewicht:
21 kDa
Proteindetails:
Gremlin-1
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody