GDF15 Antibody
Produktgrößen
100ul
£344,00
OACD03802-100UL
1ml
£955,00
OACD03802-1ML
Über dieses Produkt
- SKU:
- OACD03802
- Zusätzliche Namen:
- growth/differentiation factor 15;macrophage inhibiting cytokine-1;macrophage inhibitory cytokine 1;MIC-;MIC-1;NAG;NAG-1;SBF.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Regulates food intake; energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor; GFRAL; and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala; which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886; PubMed:28846097; PubMed:28846099; PubMed:28572090; PubMed:23468844; PubMed:29046435). On hepatocytes; inhibits growth hormone signaling (PubMed:28572090).
- Gendetails:
- growth differentiation factor 15
- Host:
- Rabbit
- Immunogen:
- Recombinant GDF15 (His193~Val296) expressed in E.coli
- Isotyp:
- IgG
- Proteindetails:
- Growth/differentiation factor 15
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Quelle:
- Polyclonal antibody preparation
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php