EIF4EBP1 Antibody
Produktgrößen
100ul
£381,00
OACD03198-100UL
1ml
£1096,00
OACD03198-1ML
Über dieses Produkt
- SKU:
- OACD03198
- Zusätzliche Namen:
- 4E-BP1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E; leading to repress translation. In contrast; hyperphosphorylated form dissociates from EIF4E; allowing interaction between EIF4G1/EIF4G3 and EIF4E; leading to initiation of translation (By similarity). Mediates the regulation of protein translation by hormones; growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (PubMed:7939721).
- Gendetails:
- eukaryotic translation initiation factor 4E binding protein 1
- Host:
- Rabbit
- Immunogen:
- Range: Ser2 - Ile117
- Isotyp:
- IgG
- Molekulargewicht:
- 12 kDa
- Proteindetails:
- Eukaryotic translation initiation factor 4E-binding protein 1
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php