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Antikörper

EBI3 Antibody

Produktgrößen
100ul
£333,00
OACD03144-100UL
1ml
£933,00
OACD03144-1ML
Über dieses Produkt
SKU:
OACD03144
Zusätzliche Namen:
cytokine receptor;EBV-induced gene 3 protein;Epstein-Barr virus induced gene 3;epstein-Barr virus-induced gene 3 protein;IL27 subunit;IL-27 subunit beta;IL27B;IL-27B;IL35 subunit;IL35B;interleukin-27 subunit beta.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Associates with IL27 to form the IL-27 interleukin; a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties; that can regulate T-helper cell development; suppress T-cell proliferation; stimulate cytotoxic T-cell activity; induce isotype switching in B-cells; and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1); type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells; binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Gendetails:
Epstein-Barr virus induced 3
Host:
Rabbit
Immunogen:
Range: Arg21 - Lys229
Isotyp:
IgG
Molekulargewicht:
25 kDa
Proteindetails:
Interleukin-27 subunit beta
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody