DTX1 Antibody
Produktgrößen
100ul
£359,00
OACD03126-100UL
1ml
£1016,00
OACD03126-1ML
Über dieses Produkt
- SKU:
- OACD03126
- Zusätzliche Namen:
- deltex 1; E3 ubiquitin ligase;deltex homolog 1;E3 ubiquitin-protein ligase DTX1;hDx-1;protein deltex-1;RING-type E3 ubiquitin transferase DTX1;RNF140.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Functions as a ubiquitin ligase protein in vivo; mediating ubiquitination and promoting degradation of MEKK1; suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling; a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch; but it also acts as a negative regulator; depending on the developmental and cell context. Mediates the antineural activity of Notch; possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis; lymphogenesis and myogenesis; and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development; suggesting that it can antagonize NOTCH1.
- Gendetails:
- deltex E3 ubiquitin ligase 1
- Host:
- Rabbit
- Immunogen:
- Range: Gly290 - His535
- Isotyp:
- IgG
- Molekulargewicht:
- 67 kDa
- Proteindetails:
- E3 ubiquitin-protein ligase DTX1
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php