DISC1 Antibody
Produktgrößen
100ul
£333,00
OACD03052-100UL
1ml
£933,00
OACD03052-1ML
Über dieses Produkt
- SKU:
- OACD03052
- Zusätzliche Namen:
- C1orf136;disrupted in schizophrenia 1 protein;SCZD9.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.55 mg/ml
- Weitere Details:
- Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis; including neuron positioning; dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role; together with PCNT; in the microtubule network formation.
- Gendetails:
- DISC1 scaffold protein
- Host:
- Rabbit
- Immunogen:
- Range: Ser102 - Cys261
- Isotyp:
- IgG
- Molekulargewicht:
- 22 kDa
- Proteindetails:
- Disrupted in schizophrenia 1 protein
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php