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Antikörper

CYP26B1 Antibody

Produktgrößen
100ul
£333,00
OACD02923-100UL
1ml
£933,00
OACD02923-1ML
Über dieses Produkt
SKU:
OACD02923
Zusätzliche Namen:
CYP26A2;Cytochrome P450 26A2;cytochrome P450 26B1;cytochrome P450 family 26 subfamily A member 1;cytochrome P450 retinoic acid-inactivating 2;cytochrome P450 retinoid metabolizing protein;cytochrome P450; family 26; subfamily B; polypeptide 1;cytochrome P450; subfamily XXVIB; polypeptide 1;P450RAI2;P450RAI-2;retinoic acid-metabolizing cytochrome;RHFCA.
Klonalität:
Polyclonal
Konzentration:
0.52 mg/ml
Weitere Details:
Involved in the metabolism of retinoic acid (RA); rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA); with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA; including 4-OH-RA; 4-oxo-RA; and 18-OH-RA. Essential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis; preventing STRA8 expression; thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells; inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development; both at the level of patterning and in the ossification of bone and the establishment of some synovial joints.
Gendetails:
cytochrome P450 family 26 subfamily B member 1
Host:
Rabbit
Immunogen:
Range: Met1 - Val512
Isotyp:
IgG
Molekulargewicht:
49 kDa
Proteindetails:
Cytochrome P450 26B1
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody