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Antikörper

CXADR Antibody

Produktgrößen
100ul
£333,00
OACD02893-100UL
1ml
£933,00
OACD02893-1ML
Über dieses Produkt
SKU:
OACD02893
Zusätzliche Namen:
46 kD coxsackievirus and adenovirus receptor (CAR) protein;CAR;CAR4/6;coxsackie virus and adenovirus receptor;coxsackievirus and adenovirus receptor;coxsackievirus B-adenovirus receptor;CVB3-binding protein;HCAR;HCVADR.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells; a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding; JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
Gendetails:
CXADR Ig-like cell adhesion molecule
Host:
Rabbit
Immunogen:
Range: Leu20 - Val229
Isotyp:
IgG
Molekulargewicht:
10 kDa
Proteindetails:
Coxsackievirus and adenovirus receptor
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody