CUBN Antibody
Produktgrößen
100ul
£355,00
OACD02866-100UL
1ml
£1005,00
OACD02866-1ML
Über dieses Produkt
- SKU:
- OACD02866
- Zusätzliche Namen:
- 460 kDa receptor;cubilin;glycoprotein 280;GP280;IFCR;intrinsic factor-cobalamin receptor;intrinsic factor-vitamin B12 receptor;MGA1.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Cotransporter which plays a role in lipoprotein; vitamin and iron metabolism; by facilitating their uptake. Binds to ALB; MB; Kappa and lambda-light chains; TF; hemoglobin; GC; SCGB1A1; APOA1; high density lipoprotein; and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia; including intestine; renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC; hemoglobin; ALB; TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
- Gendetails:
- cubilin
- Host:
- Rabbit
- Immunogen:
- Range: Cys3157 - Val3274
- Isotyp:
- IgG
- Molekulargewicht:
- 399 kDa
- Proteindetails:
- Cubilin
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php