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Antikörper

CILP Antibody

Produktgrößen
100ul
£344,00
OACD02536-100UL
1ml
£955,00
OACD02536-1ML
Über dieses Produkt
SKU:
OACD02536
Zusätzliche Namen:
9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1.
Klonalität:
Polyclonal
Konzentration:
0.45 mg/ml
Weitere Details:
Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis; and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).
Gendetails:
cartilage intermediate layer protein; nucleotide pyrophosphohydrolase
Host:
Rabbit
Immunogen:
Recombinant CILP (Pro604~His864) expressed in E.coli
Isotyp:
IgG
Molekulargewicht:
132 kDa
Proteindetails:
Cartilage intermediate layer protein 1
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody