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Antikörper

CENPF Antibody

Produktgrößen
100ul
£311,00
OACD02452-100UL
1ml
£853,00
OACD02452-1ML
Über dieses Produkt
SKU:
OACD02452
Zusätzliche Namen:
AH antigen;cell-cycle-dependent 350K nuclear protein;CENF;CENP-F kinetochore protein;centromere protein F;centromere protein F; 350/400kDa;CILD31;hcp-1;kinetochore protein CENPF;mitosin;PRO1779;STROMS.
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein; LIS1; NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed; abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression; via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia.
Gendetails:
centromere protein F
Host:
Rabbit
Immunogen:
Range: Gln436 - Lys637
Isotyp:
IgG
Molekulargewicht:
368 kDa
Proteindetails:
Centromere protein F
Aufreinigung:
Affinity Purified; Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody